---
title: Delmic Microscopy Blog | Josine Beets
description: This blog addresses the various applications and techniques to be discovered in the fields of cathodoluminescence and correlative light and electron microscopy.
---

[![](https://blog.delmic.com/hs-fs/hubfs/FAST-EM_BottleneckAutomation_Blogpost.png?width=620&name=FAST-EM_BottleneckAutomation_Blogpost.png) ](https://blog.delmic.com/sample-preparation-in-electron-microscopy-from-bottleneck-to-automated-process)

###### [fast SEM imaging](https://blog.delmic.com/topic/fast-sem-imaging)

## [Sample preparation in electron microscopy: from bottleneck to automated process](https://blog.delmic.com/sample-preparation-in-electron-microscopy-from-bottleneck-to-automated-process)

Sample preparation is crucial in electron microscopy (EM), as it influences the final data as much or maybe even more than the quality of the electron microscope. Due to its time-consuming nature, it is often seen as a bottleneck in high throughput EM of biological samples. In this post, sample preparation for EM is explained and several possible solutions are given to automate and speed up this process.

[![](https://blog.delmic.com/hs-fs/hubfs/METEOR_GuidedCryoLamellae_BlogHeader.png?width=380&name=METEOR_GuidedCryoLamellae_BlogHeader.png) ](https://blog.delmic.com/preparing-cryo-lamellae-with-the-guidance-of-meteor)

###### [cryo electron microscopy](https://blog.delmic.com/topic/cryo-electron-microscopy)

##### [Preparing cryo-lamellae with the guidance of METEOR](https://blog.delmic.com/preparing-cryo-lamellae-with-the-guidance-of-meteor)

[![](https://blog.delmic.com/hs-fs/hubfs/CRYO_LRRK2%20Tomography_Blogpost.png?width=380&name=CRYO_LRRK2%20Tomography_Blogpost.png) ](https://blog.delmic.com/resolving-the-full-structure-of-lrrk2-with-cryo-electron-tomography)

###### [life sciences](https://blog.delmic.com/topic/life-sciences)

##### [Resolving the full structure of LRRK2 with cryo-ET](https://blog.delmic.com/resolving-the-full-structure-of-lrrk2-with-cryo-electron-tomography)

[![](https://blog.delmic.com/hs-fs/hubfs/FAST_EM_Blogpost_IsletOpenAccess_NoText.png?width=380&name=FAST_EM_Blogpost_IsletOpenAccess_NoText.png) ](https://blog.delmic.com/nanotomy-large-scale-imaging-of-healthy-and-diseased-tissue)

###### [fast SEM imaging](https://blog.delmic.com/topic/fast-sem-imaging)

##### [Nanotomy: large-scale imaging of healthy and diseased tissue](https://blog.delmic.com/nanotomy-large-scale-imaging-of-healthy-and-diseased-tissue)

## Must read

- ## 1
  
  [How electron microscopy shapes the way we think, according to 6 prominent scientists](https://blog.delmic.com/how-electron-microscopy-shapes-the-way-we-think)
- ## 2
  
  [Cryo-ET imaging of SARS-CoV-2 replication organelles](https://blog.delmic.com/cryo-et-imaging-of-sars-cov-2-replication-organelles)
- ## 3
  
  [Will lead-free Perovskite solar cells lead the future?](https://blog.delmic.com/to-lead-or-not-to-lead-will-lead-free-perovskite-solar-cells-lead-the-future)
- ## 4
  
  [See More with Less: Discover the Power of METEOR 2.0](https://blog.delmic.com/introducing-meteor-2.0)
- ## 5
  
  [The case for sensitivity in integrated fluorescence microscopes](https://blog.delmic.com/the-case-for-sensitivity-in-integrated-fluorescence-microscopes)

[![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/DMVPores_Covid.png?width=380&name=DMVPores_Covid.png) ](https://blog.delmic.com/cryo-et-imaging-of-sars-cov-2-replication-organelles)

###### [life sciences](https://blog.delmic.com/topic/life-sciences)

##### [Cryo-ET imaging of SARS-CoV-2 replication organelles](https://blog.delmic.com/cryo-et-imaging-of-sars-cov-2-replication-organelles)

This year was dominated by the outbreak of SARS-CoV-2. Around the world, many researchers are looking into finding a solution for the highly pathogenic ...

[![](https://blog.delmic.com/hs-fs/hubfs/Blogpost_MotorProteins@2x.png?width=380&name=Blogpost_MotorProteins@2x.png) ](https://blog.delmic.com/cryo-electron-tomography-imaging-flagellar-motor-protein-structures)

###### [life sciences](https://blog.delmic.com/topic/life-sciences)

##### [Cryo-electron tomography: imaging flagellar motor protein structures](https://blog.delmic.com/cryo-electron-tomography-imaging-flagellar-motor-protein-structures)

Flagella are filamentous protein complexes found on many bacteria and some eukaryotic cells. Imaging techniques such as cryo-electron tomography (cryo-ET), are ...

[![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/FAST-EM_InvasionMetasisCascade_Website.png?width=380&name=FAST-EM_InvasionMetasisCascade_Website.png) ](https://blog.delmic.com/when-3d-electron-microscopy-meets-cancer-research)

###### [fast SEM imaging](https://blog.delmic.com/topic/fast-sem-imaging)

##### [When 3D electron microscopy meets cancer research](https://blog.delmic.com/when-3d-electron-microscopy-meets-cancer-research)

The increased use of 3DEM in the fields of cell biology and diagnostic pathology is due to the fact that it is one of the most accurate ways to get an overview ...

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[![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/connectomics%20blog.png?width=380&name=connectomics%20blog.png) ](https://blog.delmic.com/connectomics-imaging-large-data-in-limited-time)

###### [fast SEM imaging](https://blog.delmic.com/topic/fast-sem-imaging)

##### [Connectomics: imaging large data in limited time](https://blog.delmic.com/connectomics-imaging-large-data-in-limited-time)

The brain is probably the most complex organ in our body. One of the most fascinating challenges neuroscience faces today is mapping the complete connectivity ...