--- title: Delmic Microscopy Blog | Lucyna Włodarczyk description: This blog addresses the various applications and techniques to be discovered in the fields of cathodoluminescence and correlative light and electron microscopy. --- [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/2022_METEOR_Autophagy%20Research_Website.png?width=620&name=2022_METEOR_Autophagy%20Research_Website.png) ](https://blog.delmic.com/revealing-the-ultrastructure-of-autophagic-membranes-at-different-stages-of-biogenesis-with-correlative-cryo-electron-tomography) ###### [life sciences](https://blog.delmic.com/topic/life-sciences) ## [Revealing the ultrastructure of autophagic membranes during different stages of biogenesis with correlative cryo-ET](https://blog.delmic.com/revealing-the-ultrastructure-of-autophagic-membranes-at-different-stages-of-biogenesis-with-correlative-cryo-electron-tomography) By visualizing membrane ultrastructure directly in the cells, researchers can better understand their diversity, dynamics, and role. In this blog post, we highlight a beautiful example where researchers used cryo-CLEM to reveal the ultrastructural changes in the autophagosome membrane during its biogenesis. [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/2022_FI_Pathology%20Blogpost_1.png?width=380&name=2022_FI_Pathology%20Blogpost_1.png) ](https://blog.delmic.com/advancing-pathology-with-3d-high-throughput-nanoscale-imaging) ###### [life sciences](https://blog.delmic.com/topic/life-sciences) ##### [Advancing pathology with 3D high-throughput nanoscale imaging](https://blog.delmic.com/advancing-pathology-with-3d-high-throughput-nanoscale-imaging) [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/2022_Cryo_Cameras%20CryoFLM_Website.jpg?width=380&name=2022_Cryo_Cameras%20CryoFLM_Website.jpg) ](https://blog.delmic.com/how-to-choose-a-suitable-camera-for-cryo-fluorescence-light-microscopy) ###### [life sciences](https://blog.delmic.com/topic/life-sciences) ##### [How to choose a suitable camera for cryo-fluorescence light microscopy?](https://blog.delmic.com/how-to-choose-a-suitable-camera-for-cryo-fluorescence-light-microscopy) [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/2022_FI_Fast-EM%20Data%20management_Website.png?width=380&name=2022_FI_Fast-EM%20Data%20management_Website.png) ](https://blog.delmic.com/fast-em-data-management-platform) ###### [life sciences](https://blog.delmic.com/topic/life-sciences) ##### [Managing the exceedingly rich amount of data from the Delmic’s ultra-fast scanning electron microscope](https://blog.delmic.com/fast-em-data-management-platform) ## Must read - ## 1 [How electron microscopy shapes the way we think, according to 6 prominent scientists](https://blog.delmic.com/how-electron-microscopy-shapes-the-way-we-think) - ## 2 [Cryo-ET imaging of SARS-CoV-2 replication organelles](https://blog.delmic.com/cryo-et-imaging-of-sars-cov-2-replication-organelles) - ## 3 [Will lead-free Perovskite solar cells lead the future?](https://blog.delmic.com/to-lead-or-not-to-lead-will-lead-free-perovskite-solar-cells-lead-the-future) - ## 4 [See More with Less: Discover the Power of METEOR 2.0](https://blog.delmic.com/introducing-meteor-2.0) - ## 5 [The case for sensitivity in integrated fluorescence microscopes](https://blog.delmic.com/the-case-for-sensitivity-in-integrated-fluorescence-microscopes) [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/2022_Cryo_Crosstalk%20Blogpost_Website.png?width=380&name=2022_Cryo_Crosstalk%20Blogpost_Website.png) ](https://blog.delmic.com/overcoming-artifacts-in-cryogenic-fluorescence-microscopy) ###### [life sciences](https://blog.delmic.com/topic/life-sciences) ##### [Overcoming artifacts in cryogenic fluorescence microscopy](https://blog.delmic.com/overcoming-artifacts-in-cryogenic-fluorescence-microscopy) Cryogenic fluorescence microscopy (cryo-FLM) combined with scanning electron microscopy (SEM) makes the process of lamella milling in the cryo-electron ... [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/2022_CL_Healthy%20Sustainable%20Future_Plastics%201_Blogpost.jpg?width=380&name=2022_CL_Healthy%20Sustainable%20Future_Plastics%201_Blogpost.jpg) ](https://blog.delmic.com/how-can-cathodoluminescence-contribute-to-a-healthier-and-more-sustainable-future) ###### [materials science](https://blog.delmic.com/topic/materials-science) ##### [How can cathodoluminescence contribute to a healthier and more sustainable future?](https://blog.delmic.com/how-can-cathodoluminescence-contribute-to-a-healthier-and-more-sustainable-future) Understanding how different materials work and knowing their properties has been a keystone in human progress. In our efforts to build an environmentally ... [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/2022_Cryo_Webinar_CERES%20IS%20Ice%20Growth_Website.png?width=380&name=2022_Cryo_Webinar_CERES%20IS%20Ice%20Growth_Website.png) ](https://blog.delmic.com/protecting-lamellae-from-ice-contamination-especially-during-the-fine-polishing-step-in-the-cryo-et-workflow) ###### [life sciences](https://blog.delmic.com/topic/life-sciences) ##### [Protecting lamellae from ice contamination during milling in the cryo-ET workflow](https://blog.delmic.com/protecting-lamellae-from-ice-contamination-especially-during-the-fine-polishing-step-in-the-cryo-et-workflow) Sample milling is a crucial step in the Cryo-ET workflow. Unfortunately, this step poses yet another occasion for ice contamination to derail efforts to obtain ... ### Receive the latest updates in your mail [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/FAST-EM_Automation_Website.png?width=380&name=FAST-EM_Automation_Website.png) ](https://blog.delmic.com/electron-microscopy-workflow-meets-automation) ###### [life sciences](https://blog.delmic.com/topic/life-sciences) ##### [Electron microscopy workflow meets Automation](https://blog.delmic.com/electron-microscopy-workflow-meets-automation) With more than 90 years of development, electron microscopy is now a mature, well-established technique applied in many life science fields, such as pathology, ... [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/Cryo_Muscle%20Proteins%203D%20Tomography_Website.png?width=380&name=Cryo_Muscle%20Proteins%203D%20Tomography_Website.png) ](https://blog.delmic.com/uncovering-3d-molecular-organization-and-interactions-between-muscle-proteins-using-in-situ-cryo-electron-tomography) ###### [life sciences](https://blog.delmic.com/topic/life-sciences) ##### [Uncovering 3D molecular organization and interactions between muscle proteins using in situ cryo-electron tomography](https://blog.delmic.com/uncovering-3d-molecular-organization-and-interactions-between-muscle-proteins-using-in-situ-cryo-electron-tomography) There are more than 150 known musculoskeletal conditions (1), many of which affect specifically skeletal muscles and can lead to lifelong disabilities or even ... [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/CERES_Clean%20Station_Blogpost_Website.png?width=380&name=CERES_Clean%20Station_Blogpost_Website.png) ](https://blog.delmic.com/how-to-keep-the-cryo-em-sample-clean-and-safe-during-sample-preparation-process) ###### [life sciences](https://blog.delmic.com/topic/life-sciences) ##### [How to keep the cryo-EM sample clean and safe during sample preparation process?](https://blog.delmic.com/how-to-keep-the-cryo-em-sample-clean-and-safe-during-sample-preparation-process) Cryo-EM research helps us understand how the world works on a microscale. Often these insights have a great impact on our lives, for example, the understanding ... [![](https://blog.delmic.com/hs-fs/hubfs/Website/Blog/CERES_Vitri%20Lock%20Blogpost_Website.png?width=380&name=CERES_Vitri%20Lock%20Blogpost_Website.png) ](https://blog.delmic.com/how-to-minimize-ice-formation-during-sample-transfer-in-cryo-et) ###### [life sciences](https://blog.delmic.com/topic/life-sciences) ##### [How to minimize ice formation during sample transfer in cryo-ET?](https://blog.delmic.com/how-to-minimize-ice-formation-during-sample-transfer-in-cryo-et) Sample transfer is definitely not the most spectacular part of the cryo-ET workflow. And yet, it is one of the most problematic steps, disturbing many ...