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When choosing the most suitable camera for a cryo-fluorescence system to be applied in cryo-electron tomography (cryo-ET), it is important to consider several ...

Traditionally, scanning electron microscopy (SEM) data management has involved data transfer from a microscope to a hard disc and then loading the data to a ...

Cryogenic fluorescence microscopy (cryo-FLM) combined with scanning electron microscopy (SEM) makes the process of lamella milling in the cryo-electron ...

Sample milling is a crucial step in the Cryo-ET workflow. Unfortunately, this step poses yet another occasion for ice contamination to derail efforts to obtain ...

With more than 90 years of development, electron microscopy is now a mature, well-established technique applied in many life science fields, such as pathology, ...

There are more than 150 known musculoskeletal conditions (1), many of which affect specifically skeletal muscles and can lead to lifelong disabilities or even ...

Cryo-EM research helps us understand how the world works on a microscale. Often these insights have a great impact on our lives, for example, the understanding ...

Sample transfer is definitely not the most spectacular part of the cryo-ET workflow. And yet, it is one of the most problematic steps, disturbing many ...

Cryo-electron tomography (cryo-ET) is an extremely powerful technique that allows studies of the cellular landscape at high resolution in a near-native state.

Do you know how an integrated cryogenic fluorescent light microscope can streamline the cryo-ET workflow for targeted lamella milling of HeLa and yeast cells? ...

There is an increasing number of institutes that are starting to employ cryo-EM. However, many challenges are involved and specimen preparation is still a ...

One of the biggest hurdles in the current cryo-ET workflow is avoiding ice contamination of the vitreous sample, which is difficult to avoid due to the many ...