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There are more than 150 known musculoskeletal conditions (1), many of which affect specifically skeletal muscles and can lead to lifelong disabilities or even premature death (2). In order to develop medical treatments, it is critical to understand how healthy and impaired muscles work on the molecular level.
Do you know how an integrated cryogenic fluorescent light microscope can streamline the cryo-ET workflow for targeted lamella milling of HeLa and yeast cells? ...
Single particle cryo-electron microscopy (cryo-EM) is a powerful method to determine near-atomic structures of macromolecular complexes. In recent years this ...
The cryo-ET workflow is labour intensive and requires specialized equipment and expertise. One of the biggest hurdles in the current Cryo-ET workflow is ...
METEOR, our integrated top down fluorescence light microscope (FLM) increases lamella sample preparation for cryo-electron tomography imaging (cryo-ET). This ...
In our previous blogposts we discussed different applications of cryogenic electron tomography (cryo-ET) and how an integrated fluorescent light microscope ...
Cryo-electron tomography (cryo-ET) allows the 3D visualization of a small volume of a vitreous biological sample with nanometer resolution. Protein complexes ...
Cryo-electron tomography (cryo-ET) is an emerging technique that allows scientists to determine the structure of biological complexes within their cellular ...
Cryo-electron tomography (ET) in combination with cryo-focused ion beam (FIB) milling allows the study of biological structures in near native conditions at a ...
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