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life sciences
Focused ion beam sample preparation for cryo-electron tomography

Cryo-electron tomography (cryo-ET) is an extremely powerful technique that allows studies of the cellular landscape at high resolution in a near-native state. ...

life sciences
Resolving the full structure of LRRK2 with cryo-ET

Parkinson's disease (PD) is a neurodegenerative disease that mainly affects the motor system and its functioning. About one tenth of patients with PD has ...

life sciences
Cryo-ET imaging of SARS-CoV-2 replication organelles

This year was dominated by the outbreak of SARS-CoV-2. Around the world, many researchers are looking into finding a solution for the highly pathogenic ...

life sciences
Cryo-electron tomography: imaging flagellar motor protein structures

Flagella are filamentous protein complexes found on many bacteria and some eukaryotic cells. Imaging techniques such as cryo-electron tomography (cryo-ET), are ...

life sciences
Data handling in large-scale electron microscopy

The development of high throughput electron microscopy techniques in the last decade has made increasingly large imaging projects possible. Now that systems ...

life sciences
How can an optimized cryo-ET workflow benefit membrane trafficking research?

Eukaryotic cells contain a complex network of membrane-bound organelles where specialized processes of the cell take place.

life sciences
How can fast electron microscopy maintain both context and high resolution in large projects?

Comparing the morphology of healthy and diseased cells or tissues or examining the effect of drug treatments is extremely important for understanding of the ...

life sciences
How can an optimized cryo-ET workflow benefit the research of viral infection?

Viruses are microscopic infectious agents that are not able to reproduce outside of their hosts. We associate viruses with a variety of diseases, ranging from ...

life sciences
Electron volume microscopy to unveil interaction networks in biological specimens

As we all know, biological creatures are highly complex and three-dimensional. Therefore, it is crucial to capture 3D images of their cell structures to find ...

life sciences
How to image the beta cells in the islets of Langerhans fast and clearly?

Over the past decades, researchers have been dedicated to studying the beta cells in the islets of Langerhans in order to better understand Diabetes Type 1, ...

life sciences
An inside look at the department of Imaging Physics, TU Delft: The breeding ground for innovations in iCLEM

Understanding the relationship between structure and function in biology requires continuous developments in the field of microscopy.

life sciences
Overcoming the challenges of light microscopy in the life sciences

In order to make new discoveries in the life sciences, innovations need to be continuously made in microscopy. This way, scientists can take an ever-closer ...

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Life science Frame 264(3)

Solutions
  • METEOR
  • FAST-EM
  • CERES Ice Shield
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Workflows
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Materials analysis Frame 264(3)

Solutions
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  • JOLT 2.0
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Techniques
  • Cathodoluminescence
Applications
  • Geology
  • Semiconductors
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Insights Frame 264(3)

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Company Frame 264(3)

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