Cathodoluminescence imaging on quartz in sandstone

Delmic

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Integrated correlative light and electron microscopy: A new technique for geological materials

Posted by Delmic on May 3, 2018 3:00:00 PM

Integrated correlative light and electron microscopy (iCLEM) is a technique, in which both fluorescence imaging and electron imaging can be performed on one instrument without needing to transfer the sample. Correlative microscopy approach is being used worldwide for cancer research, in marine biology, neuroscience, and cell biology. Recently this technique has also been applied in the field of geology to gain an insight into the sedimentary organic matter in geological materials.

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Topics: correlative microscopy, Presentation, Geology, SECOM, fluorescence microscopy, electron microscopy, iclem, scanning electron microscope, correlative light and electron microscopy, geological materials


How Does Correlative Microscopy Work?

Posted by Delmic on Apr 13, 2018 1:30:00 PM

Nowadays it has become crucial for life scientists to gain structural and functional data about the sample in order to understand the biological processes happening at the scale of the nanometer. Light or fluorescence microscopy made it possible for the researchers to detect the functional information and image different colors and parts of the cell. It provides the data to understand the dynamics of the cell, however, the diffraction limit of light doesn’t allow distinguishing objects that are smaller than the wavelength of light. That is when the life scientists turn to electron microscopy, which provides the structural information in a high resolution.

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Topics: correlative microscopy, SECOM, video, clem, correlative light electron microscope, microscopy solution, integrated clem, fluorescence microscopy, electron microscopy, iclem, life science microscope, scanning electron microscope, correlative light and electron microscopy, clem video


Possibilities of the SPARC for time-resolved cathodoluminescence

Posted by Delmic on Mar 13, 2018 9:19:40 AM

What is a time-resolved cathodoluminescence? How can it be applied in different fields? In the new video Toon Coenen, application specialist at Delmic, gives an explanation of this imaging technique.

 

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Topics: cathodoluminescence, SPARC, cathodoluminescence sem, video, cathodoluminescence video, time-resolved cathodoluminescence, optical modules


Correlative light and electron microscopy on SECOM platform: benefits for the research

Posted by Delmic on Feb 21, 2018 2:44:38 PM

How can your research benefit from correlative light and electron microscopy? Why is this technique becoming increasingly attractive to many scientists in different fields of research? This is the main focus of the newest video, in which our application specialist Sangeetha Hari explains the main advantages of correlative light and electron microscopy on the SECOM, a unique microscopy solution for life sciences

 

 

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Topics: correlative microscopy, SECOM, video, clem, correlative light electron microscope, microscopy solution, integrated clem, fluorescence microscopy, electron microscopy, iclem, life science microscope, scanning electron microscope, correlative light and electron microscopy, clem video


3 outstanding advantages of the SPARC cathodoluminescence system (video)

Posted by Delmic on Jan 31, 2018 2:31:10 PM

In this short video about the SPARC our application specialist Toon Coenen talks about the main three advantages of this cathodoluminescence system. What are the possibilies of the SPARC and why cathodoluminescence is gaining poplarity in various scientific fields? Find out from the video!

 

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Topics: cathodoluminescence, SPARC, cathodoluminescence sem, video, cathodoluminescence video


An inside look at the department of Imaging Physics, TU Delft: The breeding ground for innovations in iCLEM

Posted by Delmic on Sep 28, 2017 4:29:42 PM

Understanding the relationship between structure and function in biology requires continuous developments in the field of microscopy. While electron microscopes and fluorescence microscopes have been go-to techniques for studying organic samples at a high resolution, individually they fall short in offering the exhaustive data needed for truly in-depth life science research.

In 2011, the Charged Particle Optics group at TU Delft completed the development of the SECOM. This system integrates a light and electron microscope, thus combining the labelling capabilities of fluorescence microscopy with the high-resolution nanoscale data obtained from electron microscopy. Six years later, the department of Imaging Physics houses no less than five SECOM systems.

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Topics: correlative microscopy, life sciences, microscopy, SECOM


Thoughts on the various applications, techniques, and complications to be discovered in the fascinating fields of both cathodoluminescence and correlative light and electron microscopy.

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