life sciences

Cryo-ET imaging of SARS-CoV-2 replication organelles

This year was dominated by the outbreak of SARS-CoV-2 or severe acute respiratory syndrome coronavirus 2. Around the world many researchers are looking into finding a solution for the highly pathogenic β-coronavirus, COVID19. This post will shed some light on how cryo-electron tomography (cryo-ET) and subtomogram averaging were used in studies to characterize the structure and the replication mechanism of SARS-CoV-2.